Last week I was informed of a customer who had a Purple Screen of Death on a Dell PowerEdge R810 running ESXi 4.1 Update 1.  The stop screen showed the following reason:
LINT1 motherboard interrupt. This is a hardware problem: please contact your hardware vendor
After working with Dell tech support, the customer was directed to disable the C States and C1E settings in the BIOS.  I was interested in this setting as I have a cluster using the same hardware with the same version of ESXi.
The following article describes C States and specifically the C1E setting; it is a method to reduce power consumption by powering off cores when not in use:  http://www.delltechcenter.com/page/Impact+of+C1E+on+PowerEdge+11G+Servers+–+HPBD+100909.  
The VMware Performance Best Practices Guide (available here: http://www.vmware.com/pdf/Perf_Best_Practices_vSphere4.0.pdf) specifically states on page 15 to “Disable C1E halt state in the BIOS.”  
I don’t spend a lot of time changing settings in the BIOS, but with the possible impact of this setting thought this was worth sharing.